Freeman KG, Mondal S, Macale LS, White SJ, Podgorski J, Silva B, Ortiz V, Huet A, Narsico JT, Ho M-C, Lowary T, Conway JF, Park D & Hatfull GF (2025) Structure and infection dynamics of mycobacteriophage Bxb1. Cell, in press.
Vergara S, Zhou X, Santiago U, Alaoui-El-Azher M, Conway JF, Sluis-Cremer N & Calero G (2024) Nat Commun 15, 10553. PMCID: PMC11618517. Structural basis of deoxynucleotide addition by HIV-1 RT during reverse transcription.
Werner Lass S, Smith BE, Camphire S, Eutsey RA, Prentice JA, Yerneni SS, Arun A, Bridges AA, Rosch JW, Conway JF, Campbell P, Hiller NL (2024) mSphere 9, e0072724. PMCID: PMC11656791. Pneumococcal extracellular vesicles mediate horizontal gene transfer via the transformation machinery.
Hansen KH, Byeon CH, Liu Q, Drace T, Boesen T, Conway JF, Andreasen M & Akbey Ü (2024) PNAS 121, e2406775121. PMCID: PMC11331129. Structure of biofilm-forming functional amyloid PSMa1 from Staphylococcus aureus.
Eren E, Watts NR, Conway JF & Wingfield PT (2024) PNAS 121, e2400426121. PMCID: PMC11126975. Myxococcus xanthus Encapsulin Cargo Protein EncD is Flavin-Binding Protein with Ferric Reductase Activity.
Luo Z, Huang Y, Batra N, Chen Y, Huang H, Wang Y, Zhang Z, Li S, Chen CY, Wang Z, Sun J, Wang QJ, Yang D, Lu B, Conway JF, Li LY, Yu AM & Li S (2024) Nat Commun. 15:255. PMCID: PMC10766965. Inhibition of iRhom1 by CD44-targeting nanocarrier for improved cancer immunochemotherapy.
Khare P, Edgecomb SX, Hamadani CM, Conway JF, Tanner EEL & Manickam DS. Nanoscale advances 6, 1853-1873, (2024). Ionic liquid-coated lipid nanoparticles increase siRNA uptake into CNS targets.
Huet A, Oh B, Maurer J, Duda RL & Conway JF (2023) Sci Adv 9, eadg8868. PMCID: PMC10275583. A symmetry mismatch unraveled: How phage HK97 scaffold flexibly accommodates a 12-fold pore at a 5-fold viral capsid vertex.
Chen Y, Huang Y, Li Q, Luo Z, Zhang Z, Huang H, Sun J, Zhang L, Sun R, Bain DJ, Conway JF, Lu B & Li S (2023) Nat Nanotechnol. 18, 193-204. PMCID: PMC9974593. Targeting Xkr8 via nanoparticle-mediated in situ co-delivery of siRNA and chemotherapy drugs for cancer immunochemotherapy.
Hawkins DEDP, Bayfield OW, Fung HKH, Grba DN, Huet A, Conway JF & Antson AA (2023) Nucleic Acids Res. 51, 7025-7035. PMCID: PMC10359639. Insights into a viral motor: the structure of the HK97 packaging termination assembly.
Podgorski JM, Freeman K, Gosselin S, Huet A, Conway JF, Bird M, Grecco J, Patel S, Jacobs-Sera D, Hatfull G, Gogarten JP, Ravantti J & White SJ (2023) Structure 31, 282-294.e5. PMCID: PMC10071307. A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability.
Khare P, Conway JF & S Manickam D (2022) Eur J Pharm Biopharm. 180, 238-250. Lipidoid nanoparticles increase ATP uptake into hypoxic brain endothelial cells.
Fung HKH, Grimes S, Huet A, Duda RL, Chechik M, Gault J, Robinson CV, Hendrix RW, Jardine PJ, Conway JF, Baumann CG & Antson AA. (2022) Nucleic Acids Res. 50, 8719-8732. PMCID: PMC9410871. Structural basis of DNA packaging by a ring-type ATPase from an archetypal viral system.
Sun D, Sang Z, Kim YJ, Xiang Y, Cohen T, Belford AK, Huet A, Conway JF, Sun J, Taylor DJ, Schneidman-Duhovny D, Zhang C, Huang W & Shi Y (2021) Nat Commun 12, 4676. PMCID: PMC8333356. Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes.
Strubbe-Rivera JO, Schrad JR, Pavlov EV, Conway JF, Parent KN & Bazil JN (2021) Sci Rep 11, 1037. PMCID: PMC7806632. The mitochondrial permeability transition phenomenon elucidated by cryo-EM reveals the genuine impact of calcium overload on mitochondrial structure and function.
Goetschius DJ, Hartmann SR, Organtini LJ, Callaway H, Huang K, Bator CM, Ashley RE, Makhov AM, Conway JF, Parrish CR & Hafenstein SL (2021) PNAS USA 118, e2025452118. PMCID: PMC8201801. High-resolution asymmetric structure of a Fab-virus complex reveals overlap with the receptor binding site.
Campbell PL, Duda RL, Nassur J, Conway JF & Huet A (2020) J Mol Biol. 432, 384-395. PMCID: PMC7575002. Mobile Loops and Electrostatic Interactions Maintain the Flexible Tail Tube of Bacteriophage Lambda.
Boatz JC, Piretra T, Lasorsa A, Matlahov I, Conway JF & van der Wel PCA (2020) J Mol Biol 432, 4722-4744. PMCID: PMC8170701. Protofilament Structure and Supramolecular Polymorphism of Aggregated Mutant Huntingtin Exon 1.
Huet A, Huffman JB, Conway JF & Homa FL (2020) J Virol 94, e01534-20. PMC7925205. Role of the herpes simplex virus CVSC proteins at the capsid portal vertex.
Spiriti J, Conway JF & Zuckerman DM (2020) Biophys J. 119, 1781-1790. PMCID: PMC7677133. Should Virus Capsids Assemble Perfectly? Theory and Observation of Defects.
Huet A, Duda RL, Boulanger P & Conway JF (2019) PNAS 116, 21037-21046. PMCID: PMC6800373. Capsid expansion of bacteriophage T5 revealed by high resolution cryoelectron microscopy.
Hua J, Huet A, Lopez CA, Toropova K, Pope WH, Duda RL, Hendrix RW & Conway JF (2017) mBio 8, e01579-17. PMCID: PMC5646251. Capsids and genomes of jumbo-sized bacteriophages reveal the evolutionary reach of the HK97 fold.
Stevenson HP, Lin G, Barnes CO, Sutkeviciute I, Krzysiak T, Weiss SC, Reynolds S, Wu Y, Nagarajan V, Makhov AM, Lawrence R, Lamm E, Clark L, Gardella TJ, Hogue BG, Ogata CM, Ahn J, Gronenborn AM, Conway JF, Vilardaga JP, Cohen AE & Calero G (2016) Acta Crystallogr D Struct Biol 72, 603-615. PMCID: PMC4854312. Transmission electron microscopy for the evaluation and optimization of crystal growth.
Lee H, Shingler KL, Organtini LJ, Ashley RE, Subramanium S, Makhov AM, Conway JF & Hafenstein S (2016) Science Advances 2, e1501929. PMCID: PMC4996645. The novel asymmetric entry intermediate of a picornavirus captured with nanodiscs.
Huet A, Makhov AM, Huffman JB, Vos M, Homa FL & Conway JF (2016) Nat Struct Mol Biol 23, 531-539, 2016. PMCID: PMC4899274. Extensive subunit contacts underpin herpesvirus capsid stability and interior-to-exterior allostery.
Shingler KL, Cifuente JO, Ashley RE, Makhov AM, Conway JF & Hafenstein S (2015) J Virol 89, 1900-1908. PMCID: PMC4300772. The enterovirus 71 procapsid binds neutralizing antibodies and rescues virus infection in vitro.
Shingler KL, Yoder JL, Carnegie MS, Ashley RE, Makhov AM, Conway JF & Hafenstein S (2013) PLoS Pathog 9: e1003240. PMCID: PMC3605244. The enterovirus 71 A-particle forms a gateway to allow genome release: a cryoem study of picornavirus uncoating.
Homa FL, Huffman JB, Toropova K, Lopez HR, Makhov AM & Conway JF (2013) J Mol Biol 425, 3415-3428. PMCID: PMC3779361. Structure of the pseudorabies virus capsid: comparison with herpes simplex virus type 1 and differential binding of essential minor proteins.
Toropova K, Huffman JB, Homa FL & Conway JF (2011) J Virol 85, 7513-7522. PMCID: PMC3147944. The herpes simplex virus 1 UL17 protein is the second constituent of the capsid vertex-specific component required for DNA packaging and retention.
Watts NR, Conway JF, Cheng N, Stahl SJ, Steven AC & Wingfield PT (2011) J Mol Biol 409, 202-213. PMCID: PMC3095675. Role of the propeptide in controlling conformation and assembly state of hepatitis B virus e-antigen.
Conway JF, Watts NR, Belnap DM, Cheng N, Stahl SJ, Wingfield PT & Steven AC (2003) J Virol 77, 6466-6473. PMCID: PMC155010. Characterization of a conformational epitope on hepatitis B virus core antigen and quasiequivalent variations in antibody binding.
Conway JF, Wikoff WR, Cheng N, Duda RL, Hendrix RW, Johnson JE & Steven AC (2001) Science 292, 744-748. PMID: 11326105. Virus maturation involving large subunit rotations and local refolding.
Conway JF & Steven AC (1999) J Struct Biol 128, 106-118. PMID: 10600565. Methods for reconstructing density maps of single particles from cryoelectron micrographs to subnanometer resolution.
Conway JF, Cheng N, Zlotnick A, Wingfield PT, Stahl SJ & Steven AC (1997) Nature 386, 91-94, PMID: 9052787. Visualization of a 4-helix bundle in the hepatitis B virus capsid by cryo-electron microscopy.